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Perfect medical marketing relies heavily on a medical websites design and content.? Physician?s representation in a medical website is a very classy manner, so their internet site should appear very conservative and contain only respectable content.? If your website looks like it put together by a high school student, prospective patients may assume the same of your practice.? Finding the website may not be too difficult, but appealing to those who come across it requires skill.? Having a good position in the world is vital for a physician of any specialty, but their place in the World Wide Web can be just as important.
?With the power of the World Wide Web at our fingertips we are able to tell the world who we are and exactly what we have to offer, and any interested parties are likely to follow up.? Once we have created a loyal and satisfied customer base, we can depend on those individuals to spread the word even more.? Recommendations, testimonials, and link sharing on the web are all a part of this type of advertising.? More and more people are turning to the internet to find out what others have to say about local healthcare professionals before they make an appointment.? No amount of great news can convince skeptics of your fantastic services if, however, your site suffers from poor medical websites design.
?Potential and existing clients like finding their physicians and dentists through the internet.? After you have been, located potential patients will want to read up on your company and all you have accomplished.? People are more likely to go somewhere they know a bit about, even if it is not all great, over a place they know nothing about at all.? Receiving healthcare can be a make people very nervous, and they seek comfort in knowledge by learning as much as they can about who they are dealing with.? This is the very reason why a professional and informative website is vital to your practice.
?Now, what is more important than what your future patients see is making sure that they actually see it?? Most factors of internet marketing are invisible to the naked eye.? Many various things are present into a site to ensure that it appears in the appropriate list of search engine results.? Having your website listed at the beginning of a search results page makes you the optimal choice in the eyes of most.
?There is some harsh competition out there in the world today and not much to make it any easier, but a great internet marketing campaign can definitely give you the edge.? The world does not usually perceive the medical field as one that would improve from internet marketing.? Advertising is a super important thing for any company and the internet is the best place for it.? To get your practice noticed you should hire a good medical website design company to jumpstart your online medical marketing campaign.
ScienceDaily (Nov. 29, 2012) ? An undergraduate research team analyzes peptides from fish gills to engineer antimicrobial surfaces for food preparation and medical devices.
Living in an environment teaming with bacteria and fungi, fish have evolved powerful defenses against waterborne pathogens, including antimicrobial peptides located in their gills. Undergraduate researchers at Worcester Polytechnic Institute (WPI) are studying the biology and the mechanics of one of those peptides with the hope they can use that knowledge to create engineered surfaces that kill bacteria responsible for foodborne illnesses and hospital-acquired infections.
The research team, led by Terri Camesano, professor of chemical engineering, reports its latest findings in the paper "Creating Antibacterial Surfaces with the Peptide Chrysophsin-1," published online in October by the journal ACS Applied Materials & Interfaces.
"Fish have a wonderful solution for blocking bacterial and fungal infections," Camesano said. "In this study, we are working to better understand the biochemical mechanics of that process."
As fish filter water through their gills to extract oxygen, antimicrobial peptides (AMPs), including Chrysosphin-1, trap and kill pathogens before they can invade the fish's bloodstream. Scientists in many laboratories around the world are actively exploring the potential use of these molecules to prevent human infections. In the current study, the WPI team attached AMPs to silicon and gold surfaces using two different approaches and measured the bound peptides' ability to kill the bacterial pathogen E. coli.
In the first method, the AMPs were absorbed directly onto gold and silicon crystals, forming a single layer of molecules with the AMPs lying flat on the surface. In the second method, the tips of the AMPs were attached to the surfaces with a glue-like substance so that the peptides rose vertically, like blades of grass extending up from the ground. Surfaces with both AMP configurations were cultured with E. coli cells. The results showed that when the AMPs were lying flat they killed 34 percent of the bacteria in the culture, but when they were standing up vertically they killed 82 percent.
"The hypothesis is that when peptides are attached vertically to the surfaces, they are better able to move and bend so they take on a shape that is more effective in binding to and disrupting the E.coli cells," Camesano said.
In addition to gathering data about the antibacterial efficacy of the attached AMPs, the WPI research team developed a technique for monitoring, in real time, the attachment of AMPs to surfaces. Using quartz crystal microbalance with dissipation monitoring (QCM-D), the team measured the quantity of AMPs that successfully attached to the surfaces in the horizontal and vertical orientations and the density of the AMP layers, along with other properties.
"This was a powerful process, to be able to essentially watch the binding process as it happened," Camesano said. "It is a technique that we will continue to apply in further studies."
Camesano said gold and silicon surfaces were selected for the current study because their chemical properties are well-suited for AMP binding. In ongoing work, Camesano's laboratory will continue to characterize the mechanics of AMP binding for optimal antimicrobial activity and test other materials, including titanium, stainless steel, and plastics, that would have greater utility in food preparation and healthcare.
"What is also notable about this study is that it is the work of undergraduates," Camesano said. "They've done excellent work here that will inform future graduate studies in our lab."
The WPI undergraduates who co-authored the AMP paper are Ivan Ivanov '12 (chemical engineering), Alec Morrison '12 (biochemistry), and Jesse Cobb '12 (chemical engineering). Co-author Catherine Fahey, a student at George Washington University, worked on the study during at a summer project at WPI. Their work was sponsored in large part by a grant from the National Science Foundation's Research Experiences for Undergraduates (REU) program.
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The above story is reprinted from materials provided by Worcester Polytechnic Institute.
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Journal Reference:
Ivan E. Ivanov, Alec E. Morrison, Jesse E. Cobb, Catherine A. Fahey, Terri A. Camesano. Creating Antibacterial Surfaces with the Peptide Chrysophsin-1. ACS Applied Materials & Interfaces, 2012; 4 (11): 5891 DOI: 10.1021/am301530a
Note: If no author is given, the source is cited instead.
Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.
The parents of a college freshman who was found dead on campus say they found out about her death on Facebook.
Jasmine Benjamin, a 17-year-old nursing student at Valdosta State University from Lawrenceville, Ga., was found dead in a study area in her dorm on Nov. 18. According to CBS Atlanta, police are treating the death as a homicide, pending the results of an autopsy.
Jasmine's parents say the school did not inform them of her death, learning about it instead through a friend's Facebook post.
"For someone to be so insensitive not to reach out to the family, it's very, very hurtful to say the least," James Jackson, Jasmine's stepfather, told the network.
School officials say campus police notified Gwinnett County Sheriff's Department, which then notified her parents.
Jackson said police told him that Jasmine "had been dead for at least 12 hours before she was found, because passers-by thought she was simply sleeping on the study room couch," adding to the family's frustration.
"That's the most disturbing part," Jackson said. "What kind of school is this that they know someone's laying on the couch to go check on them after a certain amount of hours?"
The parents told the Atlanta Journal-Constitution late last week that they were initially told their daughter died of natural causes. "To find out it was a homicide and that somebody actually murdered our daughter changed everything," Jackson said. "It was like hearing the news all over again."
In a statement released Monday, the university said it is "continuing to work with law enforcement agencies in their ongoing investigation."
BEIJING (Reuters) - China said on Wednesday that people should not read too much into the placement of a new map in its passports that depicts claims to disputed territory, after the United States said it would raise concerns with Beijing over the issue.
The Philippines and Vietnam have condemned the new microchip-equipped passports, saying the map they incorporate violates their national sovereignty by marking disputed waters as Chinese territory.
India, which also claims two Himalayan regions shown as Chinese territory on the map, is responding by issuing visas stamped with its own version of the borders.
"The aim of China's new electronic passports is to strengthen its technological abilities and make it convenient for Chinese citizens to enter or leave the country," Foreign Ministry spokesman Hong Lei told a daily news briefing.
"The issue of the maps in China's new passports should not be read too much into. China is willing to remain in touch with relevant countries and promote the healthy development of the exchange of people between China and the outside world."
U.S. State Department spokeswoman Victoria Nuland said the United States had concerns about China's map causing "tension and anxiety" between countries in the South China Sea.
The United States, which has urged China and its neighbors to agree on a code of conduct as a first step toward reducing tension over the South China Sea, will accept the new Chinese passports as they meet the standards of a legal travel document.
The Philippines said later on Wednesday it was taking steps to avoid any possibility of being seen to legitimize China's claims in the South China Sea.
It said it would no longer stamp visas for visitors from China in their passports but would issue them on a separate form.
"This action is being undertaken to avoid the Philippines being misconstrued as legitimizing the 9-dash-line," Edwin Lacierda, a spokesman for Philippine President Benigno Aquino, told reporters.
The "9-dash-line" refers to China's claim over the South China Sea as it depicts it on maps, including the map in the passport.
The Philippine Foreign Ministry said the decision not to stamp its visa into the Chinese passports reinforced its protest against China's "excessive claim over almost the entire South China Sea".
(Reporting by Ben Blanchard in Beijing and Manuel Mogato in Manila; Editing by Robert Birsel)
Angry protests, with attacks on Muslim Brotherhood offices in some Egyptian cities, didn't convince President Mohamed Morsi to backtrack on the sweeping powers he awarded himself over the weekend.
By Kristen Chick,?Correspondent / November 27, 2012
Egyptian protesters attend an opposition rally on Tuesday in Tahrir Square in Cairo.
Khalil Hamra/AP
Enlarge
Tens of thousands of Egyptians packed into Cairo's Tahrir Square today to protest a move by President Mohamed Morsi to remove most checks on his power.
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More than 200,000 Eqyptians massed in Cairo's Tahrir Square to protest near-absolute powers seized by President Mohammed Morsi.
In other cities, protesters clashed with the president's supporters, and broke into or set fire to the local headquarters of the Muslim Brotherhood or its political party, the Freedom and Justice Party, in at least three cities.
The Tahrir demonstrations, the biggest since President Morsi took office, were a powerful rejection of the president's decision to sideline the judiciary, which had remained nearly the only check on his power. He already holds both executive and legislative authority.?
"This decision is unjust. It makes Morsi into another dictator," says Rabab el Khatib, a doctoral student in economics, in Tahrir. She said the large turnout would force Morsi to retract the decision. "The Muslim Brotherhood must know that they are not the only ones in Egypt," she says, referring to the Islamist movement Morsi hails from. "The Egyptian people are much more than the Brotherhood. We are here, and we are strong, and we will not accept this decision."
Morsi has signaled that he won't back down, with a presidential spokesman insisting to reporters that the president's new powers are temporary and necessary to allow a constitution to be written and a parliament election.
Demonstrators reveled in the fact that they had achieved such high turnout without Islamist participation. Since Mubarak's fall, protests that do not include the Muslim Brotherhood have struggled to match the turnout of those promoted by the highly organized group. Tonight, vendors sold roasted sweet potatoes and koshari, an Egyptian pasta dish, to the crowds that included men, women, and children from across the spectrum of Egyptian society. Some said the protest reminded them of the days of the uprising that ousted former President Hosni Mubarak in February 2011.?
Protesters repeated the same chant that became famous during those protests: "The people want the fall of the regime." Some demonstrators said they had one main demand: that the president revoke the constitutional declaration that expands his power. But others called for his ouster, changing the chant to "The people want the end of Morsi's rule."
Morsi issued a constitutional declaration last week that shields his decisions from judicial review until a new constitution is in place. He also declared that the committee drafting a new constitution is immune from court rulings that might dissolve it. The president says his decision was the only way to keep Egypt on the path toward stability, and emphasized that his powers are only temporary.
Protester Ahmed Salah, a lawyer, said the decree is an assault on judicial independence. He says it concentrates too much power in Morsi's hands.
"He will be worse than Mubarak, because he wants to use his power to benefit the Muslim Brotherhood and make sure they stay in power for 50 years," he says.
Some of those in the square voted for Morsi when he ran for president against Ahmed Shafiq, the last prime minister under Mubarak. Hisham Ali said he did so because he thought it was the only way to keep the revolution alive. Now, he says, Morsi has turned against the very essence of that uprising.?
"He has turned into a dictator, like the one we came here to get rid of," he says.?
Rumors spread in the crowded square that the minister of justice or the minister of interior had resigned, and protesters called friends to check the news, shouting into their phones to be heard above the din.?
Wary of being cast as as supporters of the old regime, others chanted slogans against the "feloul," a word that literally means "remnants" and has come to represent those who were a part of or supporters of Mubarak's regime.?
The online version of the Chinese Communist Party's official newspaper appears to have fallen for a spoof by the US satirical website, The Onion.
The People's Daily ran a 55-page photo spread of North Korean leader Kim Jong-un after he was declared The Onion's Sexiest Man Alive for 2012.
He is shown riding horses, holding children and greeting his troops.
The spread is accompanied by tongue-in-cheek quotes from The Onion about the "Pyongyang-born heart-throb".
"With his devastatingly handsome, round face, his boyish charm, and his strong, sturdy frame, this Pyongyang-born heart-throb is every woman's dream come true," the People's Daily quoted The Onion as saying.
"Blessed with an air of power that masks an unmistakable cute, cuddly side, Kim made this newspaper's editorial board swoon with his impeccable fashion sense, chic short hairstyle and, of course, that famous smile."
Continue reading the main story
Chinese social media reaction
Li Kaifu, freelance journalist, on Tencent Weibo says: "It's amazing that the People's Daily doesn't know that the Onion is a satirical website. Now they are the laughing stock of the world media."
On Sina Weibo, internet user Yang Tuer writes: "All the People's Daily did was to carry this satire, and if the readers take it seriously, that's their problem. What People's Daily did wrong was to publish such meaningless content. They brought it on themselves."
Maoxu on Tencent Weibo says: "It serves them (People's Daily) right. They think a joke about Kim Jung-un is serious news. I hope the editors will now stop playing video games at work, and start looking at the world, and improving their standard. What a joke."
"I wouldn't say I'm surprised," Onion editor Will Tracy told the BBC, responding to the People's Daily feature.
"I mean, this kind of thing has happened in different forms before, so it never totally takes us by surprise, although it's a total delight whenever it does happen."
The Onion, which ran its Sexiest Man Alive piece earlier in the month, had an update to its article on Tuesday.
"For more coverage," it wrote," please visit our friends at the People's Daily in China, a proud Communist subsidiary of The Onion, Inc. Exemplary reportage, comrades."
Paper trail
By around midday on Wednesday, the People's Daily spread appeared to have been removed, with the link to the English version returning an error message.
Yuwen Wu of BBC Chinese says after The Onion published the spoof on 14 November, the story was picked up by the Hong-Kong based ifeng.com. It published a Chinese version on 21 November - but with readers' comments and a clear explanation about the satirical nature of the Onion site.
A Chinese website, Yangzi Wanbao (Yangtse Evening Daily), published a shorter version of the story on the same day, citing ifeng.com as the source, but without the crucial explanation about The Onion.
Guangming Daily then carried the story on 26 November, quoting the Yangtse Evening Daily. The People's Daily in turn published the story on 27 November, citing Guangming Daily as its source.
The Onion said previous winners of its Sexiest Man Alive prize included Syrian President Bashar al-Assad and US financial swindler Bernard Madoff, who is currently serving a 150-year prison sentence.
Two months ago, Iran's semi-official Fars news agency was forced to apologise after being taken in by a spoof news item from The Onion which declared rural Americans preferred Iranian President Mahmoud Ahmadinejad to US President Barack Obama.
It quoted one fictional West Virginian resident as saying he would rather go to a baseball game with Mr Ahmadinejad because "he takes national defence seriously".
The applicant who recently launched their preregistration and information site about .AUTO, also launched a site for their application for .FOOD. There are two other applicants for the same TLD.
And in order to avoid having to report the trickle of the other releases, here are some of the other sites for this applicant?s TLDs, which are not yet fully launched as the company informs us, since the content is not complete yet. The active sites have ?over a million pages worth of content? a company spokesperson told DNN.
Their main site at Domainia.com also allow pre-registrations for most of the TLDs applications.
See the press release after the jump.
Dot Food, LLC announces the launch of FoodDomainia.com, a pre- registration and awareness solution for the new .FOOD gTLD
Dot Food, LLC announces the launch of FoodDomainia, a pre-registration and awareness solution that introduces their applied-for gTLD, .FOOD, to businesses and consumers, worldwide.
Within the next year, the Internet Corporation for Assigned Names and Numbers (ICANN) will introduce hundreds of new, industry-specific Top Level Domains (TLD), such as .FOOD, to the Internet. The .FOOD domain extension will act as an alternative option to .COM or .NET, designed specifically to provide a commerce environment and information exchange network for the food industry. .FOOD will assist businesses in creating user friendly access to food related products, services and information instantaneously through accurate search engine classifications.
The food industry is one of the fastest growing industries in the world. As a result, food related websites have become some of the most competitive sites on the Internet. With this in mind, Dot Food, LLC is committed to educating its client base about the benefits of having a .FOOD domain extension while creating awareness among food related businesses worldwide, and maximizing pre-registration for the food industry professional or enthusiast. In addition, FoodDomainia is a gateway of information for the food industry. Along with a complete recipe and nutritional facts, the site compiles a complete U.S directory that includes all food related establishments, from farmers to grocery stores to restaurants.
By pre-registering for a .FOOD domain name on FoodDomainia, food retailers and service providers can secure a better, more professional domain name for their business, product, or service. Registrants will be instantly identified as relevant and valuable members of the food industry, will stand out among their competitors and appear stronger to online investors; all the while increasing their Search Engine Optimization.
Any Registrant that holds a trademark with the United States Patent and Trademark Office (USPTO), will have priority over any other Registrant to be awarded the applied-for .FOOD domain. Brand and trademark holders should pre-register early to protect their interest.
Dot Food, LLC is excited to participate in this new revolution of the Internet. Visit our website at www.fooddomainia.com to pre-register your .FOOD domain name, today.
Gene linked to respiratory distress in babiesPublic release date: 27-Nov-2012 [ | E-mail | Share ]
Contact: Elizabethe Holland Durando elizabethe.durando@wustl.edu 314-286-0119 Washington University School of Medicine
Some infants are more susceptible to potentially life-threatening breathing problems after birth, and rare, inherited DNA differences may explain why, according to research at Washington University School of Medicine in St. Louis.
The study is the first to identify a single gene ABCA3 that is associated with a significant number of cases of respiratory distress syndrome (RDS) in babies born at or near full term. RDS is the most common respiratory problem in newborns and the most common lung-related cause of death and disease among U.S. infants less than a year old.
Their findings will be published in the December 2012 issue of Pediatrics and are available online.
The research may lead to new diagnostic and therapeutic strategies for prevention and treatment to improve respiratory outcomes for babies.
"We found that mutations in ABCA3 account for about 10 percent of respiratory disease in babies born near their due dates," said Jennifer A. Wambach, MD, assistant professor of pediatrics and the study's lead author. "These are babies who we typically think should have mature lungs and breathe normally. While we have known for a while that RDS is a heritable disease, this is the first gene to account for a significant proportion of disease among infants that are full-term or nearly full-term."
RDS occurs when an infant's lungs don't produce enough surfactant, a liquid that coats the inside of the lungs and helps keep them open so the baby can breathe. If there isn't enough surfactant, an infant has to work hard to breathe and may suffer from a lack of oxygen. Premature infants are at especially high risk of RDS, as surfactant production increases as babies near term. However, 2 percent to 3 percent of term and near-term babies also develop RDS.
The researchers' findings suggest a range of possibilities, Wambach said. These include using the genetic knowledge to plan affected infants' births near hospitals with neonatal intensive-care units and developing medical therapies to target the abnormal protein resulting from these mutations.
Wambach said the researchers hope to identify additional genes that cause neonatal RDS and better identify babies at risk.
"But right now we're studying how these mutations function in the laboratory," Wambach said. "Statistical associations help guide us, but we also need to understand the biology of these mutations."
The research team including Aaron Hamvas, MD, and F. Sessions Cole, MD evaluated five genes known to be important for normal breathing immediately after birth. Hamvas is the James Keating Professor of Pediatrics and medical director of the newborn intensive care unit at St. Louis Children's Hospital. Cole is the Park J. White, MD, Professor of Pediatrics.
The team looked at five genes involved in the metabolism of lung surfactant by taking DNA samples from more than 500 infants of African and European descent, with and without respiratory distress, who were carried to term or near term. They evaluated the same genes in an additional 48 babies with especially severe respiratory distress to see if their findings applied to that group, and in a third group of 1,066 Missouri babies, to determine the frequency of the mutations in a general population.
In comparing babies with and without respiratory distress, they found that babies of European descent with respiratory distress were more likely to have a single mutation in ABCA3, one of the five genes tested, than the infants with no breathing problems. Babies of African descent with respiratory distress also were more likely to have single ABCA3 mutations, but this difference did not reach statistical significance.
More than one-quarter of the babies with especially severe respiratory distress had a single mutation in ABCA3. Infants who inherit two defective copies of the ABCA3 gene usually require lung transplantation for survival. However, this is the first study to show that a single mutation in ABCA3 predisposes infants to respiratory distress that can usually be treated with neonatal intensive care.
The researchers also found that 1.5 percent to 3.6 percent of babies born in Missouri carry a single ABCA3 mutation, leading the researchers to estimate that about 10 percent of RDS cases among term and near-term infants may be attributable to mutations in ABCA3.
"We picked five candidate genes and thought we would find rare mutations in all of the genes," Wambach said. "However, we found
very few mutations in the other genes, and they were not associated with RDS. Our findings were really isolated to this one gene, ABCA3."
###
Wambach JA, Wegner DJ, DePass K, Heins H, Druley TE, Mitra, RD, An P, Zhang Q, Nogee LM, Cole FS, Hamvas A. Single ABCA3 Mutations and Risk for Neonatal Respiratory Distress Syndrome. Pediatrics vol. 130 (6), December 2012
Funding for this research was received from the National Institutes of Health (NIH). Support also comes from the Eudowood Foundation, the Children's Discovery Institute, the Saigh Foundation, and Kailos Genetics. NIH grant numbers are R01 HL065174, R01 HL082747, K12 HL089968, K08 HL105891, R01 HL054703, K08 CA140720-01A1.
Washington University School of Medicine's 2,100 employed and volunteer faculty physicians also are the medical staff of Barnes-Jewish and St. Louis Children's hospitals. The School of Medicine is one of the leading medical research, teaching and patient care institutions in the nation, currently ranked sixth in the nation by U.S. News & World Report. Through its affiliations with Barnes-Jewish and St. Louis Children's hospitals, the School of Medicine is linked to BJC HealthCare.
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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Gene linked to respiratory distress in babiesPublic release date: 27-Nov-2012 [ | E-mail | Share ]
Contact: Elizabethe Holland Durando elizabethe.durando@wustl.edu 314-286-0119 Washington University School of Medicine
Some infants are more susceptible to potentially life-threatening breathing problems after birth, and rare, inherited DNA differences may explain why, according to research at Washington University School of Medicine in St. Louis.
The study is the first to identify a single gene ABCA3 that is associated with a significant number of cases of respiratory distress syndrome (RDS) in babies born at or near full term. RDS is the most common respiratory problem in newborns and the most common lung-related cause of death and disease among U.S. infants less than a year old.
Their findings will be published in the December 2012 issue of Pediatrics and are available online.
The research may lead to new diagnostic and therapeutic strategies for prevention and treatment to improve respiratory outcomes for babies.
"We found that mutations in ABCA3 account for about 10 percent of respiratory disease in babies born near their due dates," said Jennifer A. Wambach, MD, assistant professor of pediatrics and the study's lead author. "These are babies who we typically think should have mature lungs and breathe normally. While we have known for a while that RDS is a heritable disease, this is the first gene to account for a significant proportion of disease among infants that are full-term or nearly full-term."
RDS occurs when an infant's lungs don't produce enough surfactant, a liquid that coats the inside of the lungs and helps keep them open so the baby can breathe. If there isn't enough surfactant, an infant has to work hard to breathe and may suffer from a lack of oxygen. Premature infants are at especially high risk of RDS, as surfactant production increases as babies near term. However, 2 percent to 3 percent of term and near-term babies also develop RDS.
The researchers' findings suggest a range of possibilities, Wambach said. These include using the genetic knowledge to plan affected infants' births near hospitals with neonatal intensive-care units and developing medical therapies to target the abnormal protein resulting from these mutations.
Wambach said the researchers hope to identify additional genes that cause neonatal RDS and better identify babies at risk.
"But right now we're studying how these mutations function in the laboratory," Wambach said. "Statistical associations help guide us, but we also need to understand the biology of these mutations."
The research team including Aaron Hamvas, MD, and F. Sessions Cole, MD evaluated five genes known to be important for normal breathing immediately after birth. Hamvas is the James Keating Professor of Pediatrics and medical director of the newborn intensive care unit at St. Louis Children's Hospital. Cole is the Park J. White, MD, Professor of Pediatrics.
The team looked at five genes involved in the metabolism of lung surfactant by taking DNA samples from more than 500 infants of African and European descent, with and without respiratory distress, who were carried to term or near term. They evaluated the same genes in an additional 48 babies with especially severe respiratory distress to see if their findings applied to that group, and in a third group of 1,066 Missouri babies, to determine the frequency of the mutations in a general population.
In comparing babies with and without respiratory distress, they found that babies of European descent with respiratory distress were more likely to have a single mutation in ABCA3, one of the five genes tested, than the infants with no breathing problems. Babies of African descent with respiratory distress also were more likely to have single ABCA3 mutations, but this difference did not reach statistical significance.
More than one-quarter of the babies with especially severe respiratory distress had a single mutation in ABCA3. Infants who inherit two defective copies of the ABCA3 gene usually require lung transplantation for survival. However, this is the first study to show that a single mutation in ABCA3 predisposes infants to respiratory distress that can usually be treated with neonatal intensive care.
The researchers also found that 1.5 percent to 3.6 percent of babies born in Missouri carry a single ABCA3 mutation, leading the researchers to estimate that about 10 percent of RDS cases among term and near-term infants may be attributable to mutations in ABCA3.
"We picked five candidate genes and thought we would find rare mutations in all of the genes," Wambach said. "However, we found
very few mutations in the other genes, and they were not associated with RDS. Our findings were really isolated to this one gene, ABCA3."
###
Wambach JA, Wegner DJ, DePass K, Heins H, Druley TE, Mitra, RD, An P, Zhang Q, Nogee LM, Cole FS, Hamvas A. Single ABCA3 Mutations and Risk for Neonatal Respiratory Distress Syndrome. Pediatrics vol. 130 (6), December 2012
Funding for this research was received from the National Institutes of Health (NIH). Support also comes from the Eudowood Foundation, the Children's Discovery Institute, the Saigh Foundation, and Kailos Genetics. NIH grant numbers are R01 HL065174, R01 HL082747, K12 HL089968, K08 HL105891, R01 HL054703, K08 CA140720-01A1.
Washington University School of Medicine's 2,100 employed and volunteer faculty physicians also are the medical staff of Barnes-Jewish and St. Louis Children's hospitals. The School of Medicine is one of the leading medical research, teaching and patient care institutions in the nation, currently ranked sixth in the nation by U.S. News & World Report. Through its affiliations with Barnes-Jewish and St. Louis Children's hospitals, the School of Medicine is linked to BJC HealthCare.
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There is a lot of news this week in the platform-as-a-service market (PaaS), with companies like Apprenda extending its technology to offer on-premise and hybrid methods for deploying enterprise applications.
In this photo taken Saturday, Nov. 24, 2012, a giant sculpture of Gollum, a character from "The Hobbit," is displayed in the Wellington Airport to celebrate the upcoming premiere of the first movie in the trilogy, in Wellington, New Zealand. The sculpture was created at Weta Workshop, part of Peter Jackson's movie empire in the Wellington suburb of Miramar. The world premiere of "The Hobbit: An Unexpected Journey" is Nov. 28 at Wellington's Embassy Theatre. (AP Photo/Nick Perry)
In this photo taken Saturday, Nov. 24, 2012, a giant sculpture of Gollum, a character from "The Hobbit," is displayed in the Wellington Airport to celebrate the upcoming premiere of the first movie in the trilogy, in Wellington, New Zealand. The sculpture was created at Weta Workshop, part of Peter Jackson's movie empire in the Wellington suburb of Miramar. The world premiere of "The Hobbit: An Unexpected Journey" is Nov. 28 at Wellington's Embassy Theatre. (AP Photo/Nick Perry)
In this photo taken Saturday, Nov. 24, 2012, a giant sculpture of Gollum, a character from "The Hobbit," is displayed in the Wellington Airport to celebrate the upcoming premiere of the first movie in the trilogy, in Wellington, New Zealand. The sculpture was created at Weta Workshop, part of Peter Jackson's movie empire in the Wellington suburb of Miramar. The world premiere of "The Hobbit: An Unexpected Journey" is Nov. 28 at Wellington's Embassy Theatre. (AP Photo/Nick Perry)
FILE - In this Jan. 16, 2006 file photo, film director Peter Jackson arrives for the Golden Globe Awards, in Beverly Hills, Calif. Jackson launched the Weta Digital studio in 1993 with fellow filmmakers Jamie Selkirk and Richard Taylor. Named after an oversized New Zealand insect, the company later was split into its digital arm and Weta Workshop, which makes props and costumes. (AP Photo/Mark J. Terrill, File)
In this Nov. 14, 2012 photo, Weta Digital General Manager Tom Greally stands in front of a large bank of servers with the computing power of 30,000 laptops used for animation work in the companies Wellington studios in New Zealand. Weta Digital is the centerpiece of a filmmaking empire that Peter Jackson and close collaborators have built in his New Zealand hometown, realizing his dream of bringing a slice of Hollywood to Wellington. It?s a one-stop shop for making major movies - not only his own, but other blockbusters like ?Avatar? and ?The Avengers? and hoped-for blockbusters like next year?s ?Man of Steel.? (AP Photo/Nick Perry)
In this photo taken Oct. 31, 2012, Weta Digital staff celebrate Halloween in the company's Wellington studios in New Zealand. Previously never celebrated, Halloween now has a place in the region due to the large influence of Americans who come down under seeking work in the studios film making enterprises. Weta Digital is the centerpiece of a filmmaking empire that Peter Jackson and close collaborators have built in his New Zealand hometown, realizing his dream of bringing a slice of Hollywood to Wellington. It?s a one-stop shop for making major movies - not only his own, but other blockbusters like ?Avatar? and ?The Avengers? and hoped-for blockbusters like next year?s ?Man of Steel.? (AP Photo/Nick Perry)
WELLINGTON, New Zealand (AP) ? A crate full of sushi arrives. Workers wearing wetsuit shirts or in bare feet bustle past with slim laptops. With days to go, a buzzing intensity fills the once-dilapidated warehouses where Peter Jackson's visual-effects studio is rushing to finish the opening film in "The Hobbit" trilogy.
The fevered pace at the Weta Digital studio near Wellington will last nearly until the actors walk the red carpet Nov. 28 for the world premiere. But after "The Hobbit: An Unexpected Journey" hits theaters, there's more work to be done.
Weta Digital is the centerpiece of a filmmaking empire that Jackson and close collaborators have built in his New Zealand hometown, realizing his dream of bringing a slice of Hollywood to Wellington. It's a one-stop shop for making major movies ? not only his own, but other blockbusters like "Avatar" and "The Avengers" and hoped-for blockbusters like next year's "Man of Steel."
Along the way, Jackson has become revered here, even receiving a knighthood. His humble demeanor and crumpled appearance appeal to distinctly New Zealand values, yet his modesty belies his influence. He's also attracted criticism along the way.
The special-effects workforce of 150 on "The Lord of the Rings" trilogy a decade ago now numbers 1,100. Only five of Weta Digital's workers are actual employees, however, while the rest are contractors. Many accept the situation because movie work often comes irregularly but pays well. Union leaders, though, say the workers lack labor protections existing in almost any other industry.
Like many colleagues, Weta Digital's director, Joe Letteri, came to New Zealand in 2001 to work on the "Rings" trilogy for two years. The work kept coming, so he bought a house in Wellington and stayed.
"People come here because they know it's their chance to do something really great and to get it up on the screen," he said in a recent interview.
Jackson, who declined to be interviewed for this story, launched Weta in 1993 with fellow filmmakers Jamie Selkirk and Richard Taylor. Named after an oversized New Zealand insect, the company later was split into its digital arm and Weta Workshop, which makes props and costumes.
Loving homages to the craft are present in Weta Digital's seven buildings around the green-hilled suburb of Miramar. There are old-time movie posters, prop skulls of dinosaurs and apes, and a wall of latex face impressions of actors from Chris O'Donnell to Tom Cruise.
Its huge data center, with the computing power of 30,000 laptops, resembles a milk-processing plant because only the dairy industry in New Zealand knew how to build cooling systems on such a grand scale.
Little of Weta's current work was visible. Visitors must sign confidentiality agreements, and the working areas of the facilities are off-limits. The company is secretive about any unannounced projects, beyond saying Weta will be working solidly for the next two years, when the two later "Hobbit" films are scheduled to be released.
The workforce has changed from majority American to about 60 percent New Zealanders. The only skill that's needed, Letteri says, is the ability to use a computer as a tool.
Beyond having creativity as a filmmaker, Jackson has proved a savvy businessman, Letteri says.
"The film business in general is volatile, and visual effects has to be sitting right on the crest of that wave," Letteri says. "We don't get asked to do something that somebody has seen before."
The government calculates that feature films contribute $560 million each year to New Zealand's economy. Like many countries, New Zealand offers incentives and rebates to film companies and will contribute about $100 million toward the $500 million production costs of "The Hobbit" trilogy. Almost every big budget film goes through Jackson's companies.
"New Zealand has a good reputation for delivering films on time and under budget, and Jackson has been superb at that," says John Yeabsley, a senior fellow at New Zealand's Institute of Economic Research. "Nobody has the same record or the magic ability to bring home the bacon as Sir Peter."
"You cannot overestimate the fact that Peter is a brand," says Graeme Mason, chief executive of the New Zealand Film Commission. "He's built this incredible reputational position, which has a snowball effect."
Back in 2010, however, a labor dispute erupted before filming began on "The Hobbit." Unions said they would boycott the movie if the actors didn't get to collectively negotiate. Jackson and others warned that New Zealand could lose the films to Europe. Warner Bros. executives flew to New Zealand and held a high-stakes meeting with Prime Minister John Key, whose government changed labor laws overnight to clarify that movie workers were exempt from being treated as regular employees.
Helen Kelly, president of the New Zealand Council of Trade Unions, says a compromise could easily have been reached. She says the law changes amounted to unnecessary union-busting and a "gross breach" of employment laws.
"I was very disappointed at Peter Jackson for lobbying for that," she says, "and I was furious at the government for doing it."
Weta Digital's general manager Tom Greally compared it to the construction industry, where multiple contractors and mobile workers do specific projects and then move on.
Animal rights activists said last week they plan to picket the premiere of "The Hobbit" after wranglers alleged that three horses and up to two dozen other animals died in unsafe conditions at a farm where animals were boarded for the movies. Jackson's spokesman Matt Dravitzki acknowledged two horses died preventable deaths at the farm but said the production company worked quickly to improve animal housing and safety. He rejected claims any animals were mistreated or abused.
Jackson's team pointed out that 55 percent of animal images in "The Hobbit" were computer generated at Weta. The People for the Ethical Treatment of Animals (PETA) have asked Jackson in the future to create all his animals in the studio.
Controversies aside, the rise of Weta and the expat American community in and around Miramar is visible in everything from a Mexican restaurant to yoga classes. On Halloween, which in the past was not much celebrated in New Zealand, hundreds of costumed children roamed about collecting candy. Americans gave the tradition a boost here, but the locals have embraced it.
The National Business Review newspaper estimates Jackson's personal fortune to be about $400 million, which could rise considerably if "The Hobbit" franchise succeeds. Public records show Jackson has partial ownership stakes in 21 private companies, most connected with his film empire. He's spent some of his money on philanthropy, helping save a historic church and a performance theater.
For all his influence, Jackson maintains a hobbit-like existence himself, preferring a quiet home life outside of work. In the end, many say, he seems to be driven by what has interested him from the start: telling great stories on the big screen.
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Follow Nick Perry on Twitter at http://twitter.com/nickgbperry
FILE - This March 9, 2011, file photo, shows a large image of Sheik Mohammed bin Rashid Al-Maktoum, UAE Prime Minister and ruler of Dubai, rear left, and Sheik Khalifa bin Zayed Al-Nahyan, UAE President, right, on a tower at Internet City, as cars pass drive on Sheikh Zayed's highway in Dubai, United Arab Emirates. An upcoming U.N. gathering that will seek agreements on Internet oversight is raising alarms from a broad coalition of critics including the U.S. government, tech giants such as Google and rights groups concerned that changes could lead to greater efforts to filter the Web and stifle innovation for cyberspace. (AP Photo/Kamran Jebreili, File)
FILE - This March 9, 2011, file photo, shows a large image of Sheik Mohammed bin Rashid Al-Maktoum, UAE Prime Minister and ruler of Dubai, rear left, and Sheik Khalifa bin Zayed Al-Nahyan, UAE President, right, on a tower at Internet City, as cars pass drive on Sheikh Zayed's highway in Dubai, United Arab Emirates. An upcoming U.N. gathering that will seek agreements on Internet oversight is raising alarms from a broad coalition of critics including the U.S. government, tech giants such as Google and rights groups concerned that changes could lead to greater efforts to filter the Web and stifle innovation for cyberspace. (AP Photo/Kamran Jebreili, File)
DUBAI, United Arab Emirates (AP) ? An upcoming U.N. gathering about Internet oversight is raising alarms from a broad coalition of critics, including the U.S., tech giants such as Google and rights groups, concerned that changes could lead to greater efforts to censor Web content and stifle innovation in cyberspace.
Among the issues on the agenda at next month's meeting in Dubai are ideas to battle Internet spam and fraud. But also tucked into more than 1,300 proposals are potential hot-button items that opponents believe could be used by in places such as Iran and China to justify their crackdowns on bloggers and other Web restrictions.
Another likely battle when the meeting begins Dec. 3 is over European-backed suggestions to change the pay structure of the Web to force content providers ? such as Google Inc., Facebook Inc. and others ? to kick in an extra fee to reach users across borders.
It's unclear what proposals will emerge from the 11-day meeting of the U.N.'s 193-nation International Telecommunications Union, or ITU. The preliminary jockeying highlights the tensions of the Internet age between what to regulate and what to leave alone. The outcome could affect billions of Internet users.
Some are unhappy with the structure of the conference itself.
"Engineers, companies and people that build and use the Web have no vote," said Google in an online statement. "The billions of people around the globe that use the Internet, the experts that build and maintain it, should be included" in the decision-making process.
Others warn of dangers.
Simply opening the door to greater controls by the ITU raises concern among activists and others. They worry that countries with tightly controlled cyberspace such as China, Iran and Gulf Arab states will push for additions to the ITU's treaty ? such as national security monitoring ? that could be used to give legitimacy both to their current efforts to monitor and restrict the Web and to possible future clampdowns.
"We can expect an Internet totally different to today's open and global system," said Sharan Burrow, general secretary of the International Trade Union Confederation, representing 175 million workers worldwide.
"Repressive governments will have a U.N. treaty which allows them to control freedom of expression, to monitor everything any targeted individual is saying on the Net, and to stop social movements and human rights defenders demanding respect for basic rights," she cautioned.
The host United Arab Emirates, for example, sharply tightened Internet laws this month to give authorities wide powers to bring charges for offenses such as insulting the rulers or trying to organize street protests.
The ITU's secretary-general, Hamadoun Toure, said in a May speech in Canada that he expected "a light-touch regulatory approach to emerge."
The ITU says it has no interest in governing the Internet or restricting expression, but notes that it must update its communications treaty to incorporate the dramatic technological changes that have occurred since the last revisions in 1988. That was before the Internet in the public domain.
Among the topics to be discussed in Dubai: Internet security, combating fraud, preventing mobile phone "bill shock" with roaming charges and efforts to expand broadband infrastructures in developing countries.
"For every proposal, there is a counterproposal," said ITU spokeswoman Sarah Parkes.
She noted that U.N. treaties such as the Universal Declaration of Human Rights take precedence over any regulations ITU may adopt that could relate to freedom of expression.
"We will not support any effort to broaden the scope of the ITRs (International Telecommunications Regulations) to facilitate any censorship of content or blocking the free flow of information and ideas," said Terry Kramer, a former technology industry executive who was given ambassador status to lead a powerhouse 123-member U.S. delegation to the World Conference on International Telecommunications.
The groups include representatives from Facebook, Microsoft Corp., Amazon.com Inc. and Google ? which has been leading an aggressive online campaign to warn about the risks of increased Internet regulations from the meeting.
The international Internet Society, a group headquartered in Virginia and Switzerland that maintains the Internet core protocols, also claims any tighter U.N. controls could "interfere with the continued innovation and evolution of the telecommunications networks and the Internet."
The American technology company envoys in Dubai also are expected to push back strongly against any sweeping revision in Internet charges. The proposal, led by the European Telecommunications Network Operators' Association, would do away with the current system ? called "net neutrality" ? that now treats all Internet traffic equally, regardless of who is sending or receiving.
In its place, the European plan seeks to have content providers pay when their service is accessed across borders. The money raised, theoretically, could pay to expand broadband infrastructures in developing countries. Opponents, however, say companies such as Facebook could cut off access to countries where the extra charges are too burdensome.
Even the U.N.'s cultural agency, UNESCO, has raised concerns about proposals that are so broadly worded that they could be used to restrict freedom of expression under the guise of national security or fighting spam and Internet fraud.
Many thousands of traders are welcoming stock-trading robots to do the deductive work for them. This helps you to simply invest accordingly once the programme finds a good trading opportunity so you can make the cash from the exchange that you need and safely at that, but do it on your own plan and on your own time. There are some blinding trading robots out there which are rapidly changing the way that pro traders perform their analysing, too, so here is how it's possible to find one of the greatest of the finest. Personally I would recommend that you go with one of the penny share centered stocktrading robots. Why risk your cash when you have not done any research? That'd be stupid. Before making any investment choices, you have to dedicate time to finding out about the market. Trading software lets you almost invest and practice everything you have learned. There are numerous online strategies that can be employed to raise your information and experience about the market. You now do not have to fixate on the newest market reports.
No more tough forecasting about which shares to get and a lot less mistakes of which can sometimes be rather expensive. The system itself will tell you which stocks are ?winners? primarily based on its careful research into the market.
Mix this with the best securities dealing system and you have got an impressive investment tool at hand. Discipline and focus were often out playing some other place. In this time he spotted things about himself and his feelings that might impact on his trading. Everything was O.K but new he wanted help to work on some of his principles and any potential to self sabotage. A perspective coach and new tools helped him with those limiting sentiments and his capability to stay centered and trained thru any conditions.
Bad news, folks: Election Day did not erase the bitterness of partisan politics the way I fantasized it might. ("Just get us to November 6th!" I kept muttering, as if we were on the road to Oz -- instead of a long evening with Wolf Blitzer.) In fact, my Social Q's mailbox at the New York Times where I write an advice column for the Styles section, has become an even stronger magnet for the petty resentments and grand-mal seizures of folks whose political miscommunications, missed communications, and nasty communications are driving them straight up the wall.
Worse news: It's not likely to get much better as we enter the wall-to-wall holiday season -- in which greater contact with blood relations, booze, airports and credit card debt can reliably spike the blood pressures of the mildest among us.
So, here is the million dollar question: Is it even constructive to talk politics with folks who don't (and in all likelihood may never) agree with us?
Absolutely!
Until we find a rational way to stake out our differing positions -- without shouting, finger-pointing, or disrespectfully doctored GIFs of the president -- we will never build consensus or move toward the compromises that everyone knows we're desperate for. (Also, in light of this fall's lousy TV line-up and the New York Jets abysmal season to date, what else are we going to talk about?)
So, it's decided: We are going to talk politics. But how do we engineer these conversations so they're productive and polite?
Well, it all boils down to oxygen. (Yep, you heard me: oxygen)
1. Listen.
When your brother-in-law (or neighbor or boss) starts voicing political opinions that make you want to interrupt immediately -- screaming out your objections or grinding his face into a sofa cushion, simply breathe deeply, inhaling and exhaling as you listen. Keep a cool expression on your face that gives away nothing, but more importantly, keep quiet.
Letting the other person have his say is critical for two reasons: It lets him know you respect him enough to hear him out, which creating a small mountain of goodwill. But more selfishly, it creates an equitable right for you to be heard in return. I'm not saying this will be easy. But if women can breathe through the body-wracking agony of delivering twins, you can surely breathe through your neighbor's interpretation of the fiscal cliff.
This does not require you to endure political rants or nasty personal attacks. (Even listening has its limits.) When the other guy becomes screechy or his arguments ad hominem, simply toss in a mild-mannered: "Indoor voice, please" or "Let's steer clear of name-calling." If that doesn't work, retreat. It takes two to tango -- at we've all learned from Dancing With the Stars. But most times, your quiet reminder will work, and the other guy will inch back toward civility.
2. First Agree, then Make Your Own Point.
So, now that you've listened like a champ, and let the other person make his point, what then? What else: More oxygen: Take another deep breath. Let your exhale wipe away as much smirk and snark and superiority as it can. Then find one (even miniscule) thing to agree with in what your neighbor just said -- even if it's a simple: "Well, we both agree that this is an important issue." Then make your counterpoint gently but firmly, open to further discussion, but no patsy.
If the other guy interrupts you, remind him calmly that you heard him out and would like the same respect from him.
Now, keep it up: breathing and listening, breathing and speaking. Who knows? You might actually get somewhere.
3. Don't Be Afraid to Take a Break.
If this tack fails, never fear: Simply turn up the oxygen. Don't be shy about excusing yourself for a quick walk around the block. Clear your head with some nice deep breaths. And let your oxygenated breath return your pounding heart rate to normal.
When you head back inside, consider round two. But if you take up this challenge, be even gentler and more respectful the second time around -- like Daniel Day Lewis in his Abraham Lincoln drag, with a voice as calm and sure as the one that began to heal a nation even more deeply divided (and less inclined to compromise) than the talking heads at MSNBC and Fox News.
Just breathe deep -- and good luck out there.
Philip Galanes is the author of Social Q's: How to Survive the Quirks, Quandaries, and Quagmires of Today
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A New Real Estate Company, with a Twist, Opens its Doors
BY Baristanet Staff ?|? Friday, Nov 23, 2012 11:00am ?|? COMMENTS (5)
Do you know someone who?s looking to buy a home in Essex County? A new non-traditional real estate company has opened its doors in Montclair to interested buyers.
Habitat is different from traditional real estate agencies in that it only represents home buyers?never sellers?eliminating the conflict of interest that can occur when buying a home.
?Most buyers don?t realize how important it is to have proper representation in a real estate transation.? said Clayton Borchard, Broker of Record at Habitat. ?Unless the buyer signs a buyer?s agreement with an agency, the fiduciary responsibility of those showing available home will always be to the seller. Their main objective is to get the house sold. At Habitat, our main objective is to get the buyer into the house that is right for them.?
In most cases, Habitat also rebates their commission directly to clients at closing. In turn, the company charges its clients a flat fee to handle the transaction. For more on how it works, click here. You can estimate your own potential rebate with their cash back calculator on their home page.
?Habitat?s cash rebates can be significant,? said Gerald DeNicola, a Habitat agent, Montclair resident, and one of the company?s founding partners. ?On a $500,000 sales price, Habitat clients could receive up to $8,000 back at closing. What could be better than getting some cash in your pocket after making such a significant purchase??
Habitat represents buyers looking for homes in Montclair, Glen Ridge, Bloomfield, Clifton, Cedar Grove, Essex Fells, Nutley and Verona. The agency?s offices are located at Academy Square, 33 Plymouth Street, Suite 206. For more on the company, log on to their website or their Facebook page.
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Public release date: 27-Nov-2012
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There is a lot of news this week in the platform-as-a-service market (PaaS), with companies like 
Many thousands of traders are welcoming stock-trading robots to do the deductive work for them. This helps you to simply invest accordingly once the programme finds a good trading opportunity so you can make the cash from the exchange that you need and safely at that, but do it on your own plan and on your own time. There are some blinding trading robots out there which are rapidly changing the way that pro traders perform their analysing, too, so here is how it's possible to find one of the greatest of the finest. Personally I would recommend that you go with one of the penny share centered stocktrading robots. Why risk your cash when you have not done any research? That'd be stupid. Before making any investment choices, you have to dedicate time to finding out about the market. Trading software lets you almost invest and practice everything you have learned. There are numerous online strategies that can be employed to raise your information and experience about the market. You now do not have to fixate on the newest market reports. 
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Do you know someone who?s looking to buy a home in Essex County? A new non-traditional real estate company has opened its doors in Montclair to interested buyers.